Study on the Changes of Antibody IgM and IgG Based on the Plasma Treatment of COVID-19 in Patients with New Coronary Pneumonia
Duan Li,
Qin Ying,
Li Yuanda,
Zhang Chi,
Qu Xiaojuan,
Wang Zifan,
Baishan•Hunapiya,
Wang Fan,
Lin Zhiqiang,
Lin Guoyue
Issue:
Volume 10, Issue 1, February 2022
Pages:
1-6
Received:
7 January 2022
Accepted:
Published:
8 January 2022
Abstract: Objective To apply the convalescent plasma of recovered patients with new coronary pneumonia to treat COVID-19 to explore the changes of antibodies IgM and IgG in their bodies and the therapeutic effect. Methods Plasma treatment was performed for COVID-19, and the values of antibody IgM and IgG ct were observed and statistically analyzed. Results (1) 99 cases of rapid development, severe and critically ill patients were transfused with 107250ml plasma, 1083.33ml per capita. The effective rate of blood transfusion was 100% and the cure rate was 100%. (2) The 229 bags of convalescent plasma of the infused convalescent patients have an IgG ct value of 31.61±23.28 and an IgM of 7.19±11.94. (3) The antibody IgG and IgM ct values (68.70±69.14 and 47.89±64.63) of patients in the blood transfusion group were higher than the pre-transfusion ct values (4.46±13.99 and 4.46±13.99), and the differences were significant (p<0.05); The antibody IgM and IgG ct values at discharge of the non-transfusion group were higher than the antibody ct values at admission (p<0.05); in general, the IgM and IgG antibody ct values of the blood transfusion group were 1-3 times higher than those of the non-transfusion group, and there was no difference ( p>0.05), but the levels of antibody IgG and IgM in severe patients in the blood transfusion group were significantly higher than those in the non-transfusion group (P<0.05). (4) The hospitalization days of the fast-growing and severe patients in the blood transfusion group were significantly shorter than those in the non-transfusion group (P<0.05). Conclusion The application of convalescent plasma from patients recovering from new coronary pneumonia to treat COVID-19 can greatly increase the antibody content in severe and critically ill patients, effectively enhance immune function, shorten the length of hospital stay, and speed up the early improvement of the disease.
Abstract: Objective To apply the convalescent plasma of recovered patients with new coronary pneumonia to treat COVID-19 to explore the changes of antibodies IgM and IgG in their bodies and the therapeutic effect. Methods Plasma treatment was performed for COVID-19, and the values of antibody IgM and IgG ct were observed and statistically analyzed. Results (...
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Innovative Practice of Key Technologies in Nucleic Acid Detection Laboratory of Gas Membrane Building Structure
Chen Wurong,
Su Yunsheng,
Chen Zhaorong,
Li Wenqi,
Yin Ye,
Wen Lijuan,
Li Ruoyu,
Chen Weijun
Issue:
Volume 10, Issue 1, February 2022
Pages:
7-16
Received:
7 January 2022
Accepted:
Published:
8 January 2022
Abstract: The novel corona-virus pneumonia outbreak that broke out at the end of 2019, and it has spread to many countries around the world, so the world's public health security is facing great challenges. As a key medical resource, nucleic acid testing laboratories directly affect the management and control capabilities of countries in response to the epidemic; there are disadvantages in the traditional laboratories for nucleic acid testing, such as high implementation costs, long construction periods, difficult installations, and difficult overall storage and transportation. In view of the rapid spread of the virus, it is particularly important to solve the problems that how to quickly provide laboratories for nucleic acid testing, which must be with fast mass production, low cost, easy installation, and convenient storage and transportation. This article introduces the importance of viral nucleic acid testing laboratories, and discusses the domestic nucleic acid testing capabilities during the epidemic and the innovative solutions of testing laboratories. An innovative design plan was proposed, the air-film structure nucleic acid testing laboratory adopted fresh air systems to achieve positive and negative pressure conversion, it equipped with intelligent technical equipment and combined with air film structure, which is rapid installation and high airtightness. The air-film structure nucleic acid testing laboratories have been successfully used in 9 countries and 26 cities in the world. The local nucleic acid testing capabilities have significantly improved, it was up to 1,000,000 single tubes a day. The newly designed laboratories have contributed to global epidemic prevention and control.
Abstract: The novel corona-virus pneumonia outbreak that broke out at the end of 2019, and it has spread to many countries around the world, so the world's public health security is facing great challenges. As a key medical resource, nucleic acid testing laboratories directly affect the management and control capabilities of countries in response to the epid...
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Optimization of Urban Industrial Development Pattern Under the Guidance of Public Transportation
Zeng Wei,
Peng Jian Dong,
Yang Hong
Issue:
Volume 10, Issue 1, February 2022
Pages:
17-24
Received:
28 February 2022
Accepted:
Published:
3 March 2022
Abstract: Urban industry is an important support for urban economic development and a driving force for the continuous improvement of people's material and cultural level. It is of great significance to shape the pattern of urban industrial development and stimulate the vitality of urban industrial development. As the most important infrastructure for the efficient operation of a city, the areas with high accessibility often become industrial agglomeration areas with active economic activities. The industrial agglomeration effect oriented by public transportation is closely related to the distribution of urban industrial pattern. Hankou historic district as an example, this article selects the regional finance, commerce, wen chong, type is extremely rich, the tourism industry has a certain representativeness and universality and actuality of hankou historic district four big industry major financial and commercial industry distribution is relatively fragmented, to upgrade industrial structure, at the same time, the tourism industry is still in its infancy, accumulative effect to mining. Through sorting out the public transportation situation of Hankou historic area, and analyzing the accessibility of stations and coverage areas, the agglomeration development of urban industrial pattern is led.
Abstract: Urban industry is an important support for urban economic development and a driving force for the continuous improvement of people's material and cultural level. It is of great significance to shape the pattern of urban industrial development and stimulate the vitality of urban industrial development. As the most important infrastructure for the ef...
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